Ozy News: How Designer Proteins Could Change Your Life
Ozy News spoke with Drs. David Baker and Ingrid Swanson Pultz about using Rosetta, a computer software program, to design novel proteins, like KumaMax. KumaMax is a uniquely engineered, recombinant enzyme that is designed to be active under acidic stomach conditions and has high specificity for the parts of gluten that trigger the autoimmune reaction leading to celiac disease.
“The potential for new proteins is really only limited by the imagination,” says Ingrid Swanson Pultz, chief scientific officer of PvP Biologics.
Ozy News says about KumaMax, “…the enzyme has enormous significance as a bioengineering standard bearer. It is one of the latest in what could emerge as an entirely new class of drugs: protein-based medicines that are built from scratch, not found in nature. Using sophisticated software, researchers are folding peptides and engineering amino acids to create drugs with a range of new capabilities.”